Abstract
BDNF is a neurotrophin with a high level of expression in the Central Nervous System (CNS). This neurotrophin acts binding in the receptor TrkB and can facilitates the neuronal survival and differentiation. BDNF also seems to play a key role in energy homeostasis since haploinsufficiency of BDNF or its receptor TrkB leads to excessive early weight gain and hyperphagia. Several lines of e…