Abstract
The aim of this cross-sectional study will be to assess the presence and to quantify subgingival periodontal pathogens in smokers and nonsmokers. Thirty heavy smokers and 30 nonsmokers with severe chronic periodontal disease will be recruited. Subjects will be matched regarding sex, age + 5 years) and periodontal pocket depth (+1mm). Smoking status will be confirmed by means of subjects´ …