CV Lattes
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Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Bacharelado em Ciências Biológicas from Universidade de São Paulo (2007), bachelor's at Licenciatura Plena em Ciências Biológicas from Universidade de São Paulo (2008) and doctorate at Biochemistry from Universidade de São Paulo (2013). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: diabetes, human islets, apoptosis, recombinant human prolactin and insulinoma. (Source: Lattes Curriculum)
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Autophagy is a conserved physiological system of intracellular degradation, it can be considered as a cytoprotective mechanism; however, autophagy is also able to promote cell death by an altered degradation of cell content. Besides its physiological effect, it has been proposed that deregulation of this process may have important roles in several diseases; its role in diabetes is still o…
Recent results from our lab have shown that in beta-cells, prolactin (PRL) leads to the upregulation of HSPB1, and that silencing its expression completely abolishes PRL's effect on cytoprotection. Moreover, by performing immunopreciptation flowed by mass spectrometry we now know that only when beta-cells were co-treated with cytokines and PRL, HSPB1 interacts with Superoxide Dismutase 1 …
| 1 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
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