Abstract
Angiotensin-II (Ang-II) plays an important role in the pathophysiology of systemic arterial hypertension (SAH). The binding of Ang-II to its AT1 receptor (AT1r) triggers a series of effects that raise blood pressure. Moreover, Ang-II plays a key role in the activation of inflammatory responses, and it is considered a peptide with powerful pro-inflammatory effects. Inflammation has also gr…