CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Laís Santos Domingues in research grants and scholarships supported by FAPESP.
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Ischemic diseases are the leading cause of mortality and morbidity worldwide. The process known as ischemia-reperfusion (I/R) causes irreparable damage to the affected tissues due to the wide variation in tissue oxygen tension. Reperfusion of the affected tissue, which had been temporarily maintained at hypoxia (low oxygen tension), results in abrupt oxygen supply (high oxygen tension) an…
Acute myocardial infarction, characterized by myocardial damage due to ischemia- reperfusion events, is an important public health problem, being considered the main cause of morbidity and mortality worldwide. We have recently reported that ischemic preconditioning, characterized by brief insults of ischemia alternating with short periods of reperfusion, can produce cardioprotection again…
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