Abstract
Approximately 3.3 billion people live at risk of contracting malaria worldwide, with 219 million cases and 660,000 deaths in 2010. In 2011 were notified 267,000 cases of the disease in Brazil. Plasmodium falciparum requires prompt and effective treatment, due to its ability to evolve to severe cases and death. Artemisinin derivatives can reach high plasma levels quickly, reducing signific…