CV Lattes
Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has experience in Pharmacy, focusing on Pharmacy, acting on the following subjects: dendritic cells, migration capacity, efferocytosis, apoptotic cells and capacidade migratória. (Source: Lattes Curriculum)
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The dynamic of immune cells to respond to foreign antigen while maintaining tolerance to self-antigens requires constant metabolic adaptation. Dendritic Cells (DC) play a crucial role in the recognition of pathogens as well as in the clearance of Apoptotic Cells (AC) during infection or injury. We have recently showed that the clearance of AC in the absence of an infection leads to tolero…
Efferocytosis by dendritic cells (DC) is one of the main sources for self-antigen presentation, which leads to generation of tolerogenic DC (tDC), characterized by low expression of MHC-II, CD86 and CCR7 molecules, and production of anti-inflammatory mediators, such as TGF-², IL-10 and PGE2, thus promoting T reg cells differentiation. Recently, studies have shown that excessive salt intak…
Dendritic cells (DC) are professional antigen-presenting cells and one of the most able to induce the activation and differentiation of naive T cells in different lymphocyte subsets : Th1 , Th2 , Th17 and Treg. In homeostatic conditions, immature DC are as well as macrophages in the tissue represent the first line of host defense against microorganisms. During the infection, immature DC p…
| 3 / 3 | Completed scholarships in Brazil |
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