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Universidade de São Paulo (USP). Instituto de Física de São Carlos (IFSC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Ana Carolina Mafud in research grants and scholarships supported by FAPESP.
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Schistosomiasis is caused by worms of genus Schistosoma. It has become one of the most fatal verminose worldwide, affecting more than 200 million people in poor neighborhoods without sanitation, being the worst neglected diseases on the planet. Schistosomiasis treatment and control are dependent upon a single drug, praziquantel, which is on the market for over three decades. Due to its co…
Schistosomiasis is caused by worms of genus Schistosoma. It has become one of the worst neglected diseases on the planet, affecting more than 200 million people in poor neighborhoods without sanitation, being the most fatal verminose worldwide. Schistosomiasis treatment and control are dependent upon a single drug, praziquantel, which is on the market for over three decades. Due to its co…
Pilocarpine is an alkaloid isolated from the leaves of Pilocarpus microphyllus (Rutaceae), a native plant from Brazil, known as jaborandi, which presents muscarinic agonist activity, and it is used as a miotic agent in the treatment of glaucoma. The alkaloid imidazole Epiisopiloturina (EPI) comprises 70% of purifying residue, with activity against Schistosma mansoni, and other compounds o…
Epiisopiloturine is an imidazole alkaloid extracted from Pilocarpus microphyllus Stapf ex Wardleworth, a Brazilian native plant, whose in vivo activity against Schistosoma mansoni led to parasite burden, to reduction in hepatosplenomegaly, the egg burden in faeces, and fell granuloma diameter. Epiisopilosine, another secondary metabolite from jaborandi, was tested in vitro (just accepted …
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 4 | All Scholarships |
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