Abstract
Chronic kidney disease (CKD) is a public health problem. In Brazil, the main causes of CKD are hypertension and diabetes mellitus. Independently of the etiology, the rule is the functional loss of the organ associated with the replacement of renal parenchyma by fibrous tissue. The activation of the renin-angiotensin aldosterone system (RAAS) is common in many renal diseases and plays a cr…