Abstract
This project deals with the synthesis, characterization and evaluation of cathepsin B inhibitory activity, involving chelated compounds of the type [{Pd(N C)X}(PR3)] {N C = C2,N-bzox, C2,N-mbz, C2,N-bzan (bzox=benzaldehydeoxime, mbz = N-benzylidenemethylamine, bzan = N-Benzylideneaniline); X = Cl or dmf; (PR3) = triphenylphosphine (PPh3), tricyclohexylphosphine (PCy3), tris(p-tolyl)phosp…