Abstract
Previous results showed the in vitro and in vivo activity of the palladacycle complex DPPE 1.2 against Leishmania (Leishmania) amazonensis. The treatment of L. (L.) amazonensis-infected BALB/c mice with DPPE 1.2 resulted in a significant decrease of lesion size and parasite load compared to those of untreated animals and no toxicity was observed in treated animals at the concentrations of…