Abstract
Aripiprazole fits in a new class of antipsychotic agents known as dopamine systems stabilizers (DSSs) that represent Dopamine D2 receptor partial agonists. Considering the already established shape and pharmacophore similarity the heterocyclic core present in the aripiprazole, dihydroquinolinone, and the heteroaromatic naphthyridone, the bioisosteric replacement of those structures is an …