CV Lattes
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Universidade de São Paulo (USP). Instituto de Química de São Carlos (IQSC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at enfermagem from Universidade do Estado do Pará (2009). (Source: Lattes Curriculum)
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This project investigates the regulatory role of phosphorylation in modulating protein-protein interactions and chaperone activity of the Hsp90/SGT and Hsp90/Aha1 complexes in Leishmania braziliensis. Hsp90 functions as a molecular chaperone, assisting in the folding, maturation, and stabilization of various client proteins, as well as integrating and coordinating crucial cellular signali…
In Brazil, snake envenomings represent a major public health problem with a high incidence of in western Pará, mainly due to Bothrops atrox. Geographical variations in the composition of the venom from this species have been reported and may be an important factor for the adaptation of the snakes to different environments and may have implications for the clinical manifestations of enveno…
Bothrops envenomation often includes local effects and systemic reactions represented mainly by coagulation disturbances. SVSPs, SVMPs, PLA2s and CTLs are main protein families involved in these disturbances. These toxins are able to act on components of the coagulation cascade, promote hemorrhage and interfere by different ways in the formation of the hemostatic plug and platelet aggrega…
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