CV Lattes
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Universidade de São Paulo (USP). Instituto de Biociências (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's in biology from Universidade Federal do Espírito Santo, UFES (2009) and PhD in biotechnology from UFES (2014). Postdoc training at the Institute of Biosciences, University of São Paulo, University of Geneva, and Boston Children's Hospital. Instructor at Boston Children's Hospital, Harvard Medical School. (Source: Lattes Curriculum)
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The MHC (Major Histocompatibility Complex) class I and II genes, also known as HLA genes in humans (Human Leukocyte Antigens), are highly polymorphic and there is a substancial body of evidence showing that they have been a target of balancing selection. In addition, these loci have also been associated with more diseases than any other region in the genome. While diversity and differenti…
The HLA genes are the most polymorphic loci of the genome, and also the most associated with disease. This places HLA genes among the most studied genes in the genome. However, their extreme polymorphism imposes challenges to methods of expression quantification, and as a consequence the study of HLA expression and regulation is still in its infancy. In our main project, we have developed…
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