CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's at Pharmaceutical Sciences from Universidade de São Paulo (2009), PhD in Medicinal Chemistry (2014), having spent one year at the Massachusetts Institute of Technology - MIT (USA). Has experience in Medicinal Chemistry, focusing on Molecular Dynamics Simulation, Multivariate Data Analysis (Hierarchic Cluster Analysis and Principal Component Analysis), QSAR and molecular docking, working mainly on the elucidation of alkylphosphocholines mechanism of actions and biophysics of lipid bilayers. (Source: Lattes Curriculum)
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AT1 receptor is part of the G protein-coupled receptors family. The angiotensin II binding leads to the activation of the heterodimeric G protein and, consequently, the activation of phospholipase C and protein kinase calcium dependent (PKC). Next, the receptor is phosphorylated by ²-arrestin and internalized. Studies have shown that ²-arrestin also generates second messengers which can a…
| 1 / 1 | Completed scholarships in Brazil |
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