Abstract
Background: recent data pointed to the role of the sonic Hedgehog (SHH) signaling pathway in adrenal cortex and capsule development and maintenance. Disruption of this pathway may be involved in adrenal tumorigenesis. Preliminary data generated in our Laboratory point to the potential involvement of SHH signaling in adrenal cortex steroidogenesis. Aim: to examine the role of the SHH pathw…