CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciencias Biologicas from Universidade Federal de Uberlândia (2006), master's at Biochemistry from Universidade Federal de Minas Gerais (2009) and doctorate at Biochemistry from Universidade Federal de Minas Gerais (2011). Has experience in Biochemistry, acting on the following subjects: signal processing, sinais, nanotechnology, multidisciplinary education and biophysics. (Source: Lattes Curriculum)
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Brazil is the third country in the world in total tons of pesticides use per year. Pesticides are toxic substances or a mixture of substances that are naturally or chemically synthesized. They are widely used in agriculture to control plagues; however, since they are toxic to life, they are inevitably toxic to humans. Heavy use of pesticides has contaminated ecosystems. In Brazil, at leas…
Currently, one of the great challenges in medical research is to model cells in vitro capable of recapitulating physiological processes in the most similar way possible to complex organisms. The difficulty of obtaining specialized cells for studies in laboratories such as cardiomyocytes, endothelial cells and neurons has always been a challenge for the development of more accurate studies…
Cardiac arrhythmia due to right heart disease is an independent predictor of death. The etiology of heart disease is known to impact therapeutic choice. Right-sided heart disease may occur from direct injury to the heart tissue, or from changing in the right heart afterload leading to later cardiac remodeling. For both types of cardiac arrhythmias due to injury of the right side of the he…
The two groups will combine their expertise to understand the sodium channel in insect physiology with the aim to develop novel green pesticides. The Chinese group is specialized in structural biology and biophysical techniques to characterize protein interactions, while the Brazilian group has extensive experience in electrophysiology and image analysis. The exchange activities will faci…
The control of cardiac rhythm is dictated by the shape of the action potential (AP), which relays on the distinct class of ion currents, among them sodium current (INa), whichever has two components, a fast and a slow inactivating current. The latter is known as late sodium current (INaL). INaL has an important role in the repolarization phase of the AP in cardiac cells and under pathophy…
Cardiovascular diseases (CVD) are the leading cause of death worldwide. According to the World Health Organization, more than 18.6 million human beings globally have died as a result of cardiovascular diseases in the year 2022. Cardiac arrhythmias are the major cause of death in patients with CVD. Recent evidence indicates that SCN10A/NaV1.8 is associated with some types of cardiac arrhyt…
In recent decades, the demand for pesticides has grown significantly. However, inappropriate use poses a serious risk to humans and wildlife. Diphenoconazole, prothioconazole and tebuconazole are all antifungal pesticides with systemic action in the triazole class, and are leaders in their class in terms of sales and use. Due to their physicochemical characteristics, they are found in soi…
Invasive or disseminated fungal infections represent a global health problem, affecting millions of patients worldwide. Currently, there are several drugs available to treat these infections, with Fluconazole being one of the most commonly used in clinical practice. It is known for its ability to inhibit ergosterol biosynthesis, leading to the death of fungi or inhibiting their growth. Ho…
(Only some records are available in English at this moment)
The use of pesticides allows meeting the food demand of today's society, but some chemical residues can persist in the environment and reach non-target organisms, leading, for example, to cardiotoxicity. Additionally, pesticide residues are found in drinking water and food, a fact that favors the daily intake of these compounds by the population. Chlorpyrifos, a type of organophosphate, h…
Cardiac Arrhythmias are among the diseases that most lead to disability and sudden death worldwide, and thyroid diseases, especially Hypothyroidism, play a prominent role. Thyroid hormones regulate the expression of myocardial genes that control intracellular calcium handling, leading to altered excitation-contraction coupling and heart function. Hypothyroidism is known to lead to a reduc…
The main function of the heart is maintained by the proper coupling of its electrical and mechanical activities, a process in which transmembrane ion channels are crucial. Among them, the channels for sodium, Nav1. 5 (main channel for cardiac sodium), encoded by the SCN5A gene, is an important regulator of cardiac myocyte excitability and, therefore, is commonly involved in cardiotoxicity…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 4 / 3 | Completed research grants |
| 7 / 7 | Ongoing scholarships in Brazil |
| 5 / 5 | Completed scholarships in Brazil |
| 18 / 17 | All research grants and scholarships |
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