Abstract
Aggregatibacter actinomycetemcomitans(Aa) is an important periodontal pathogen that may be associated with aggressive periodontitis (AP) which is characterized by rapid attachment and bone loss. Aa possesses many virulence factors that can suppress or inactivate the host immune system. Aa shows several serotypes, including serotype b that is often associated with PA. The Aa JP2 clone (ser…