CV Lattes
ResearcherID
Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas (FCM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Medicina from Universidade Estadual Paulista Júlio de Mesquita Filho (1973) and doctorate at Medicine from Universidade Estadual de Campinas (1999). Has experience in Medicine, focusing on Medicine, acting on the following subjects: fibrose cística, criança, nutrição, cystic fibrosis and fisioterapia. (Source: Lattes Curriculum)
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Cystic fibrosis (CF) is a lethal autosomal recessive disease with clinical manifestationsthat compromise the digestive, reproductive and mainly the respiratory system. It is caused bymutations in the CFTR gene encoding Cl- channel in the apical membrane of epithelial cells. It was described about 2000 mutations in CFTR and the F508del is the most frequent mutation (about 90% of patients).…
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