CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
José Augusto Cipriano Guedes in research grants and scholarships supported by FAPESP.
| News published in Agência FAPESP Newsletter about the researcher |
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The uncarboxylated form of osteocalcin (uOCN), an osteoblat-derived protein, acts as a homone that has a positive effect on insulin secretion and sensitivity, as well as on fat metabolism. These observations led to the fascinating discovery of bone as an endocrine gland. Treatment with uOCN prevents hepatic steatosis in obese animal; however, little is known about the molecular mechanism …
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