Abstract
The ST2 gene encodes a protein that is a member of the interleukin-1 receptor family and consists of two isoforms: a transmembranereceptor form (ST2L) and a soluble one (sST2), that can be detected in serum. Clinically, elevated serum levels of sST2 indicate patients with destabilized cardiac function and more ventricular remodeling, besides identifying patients with a higher risk of deat…