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Universidade Estadual Paulista (UNESP). Campus de São José do Rio Preto. Instituto de Biociências, Letras e Ciências Exatas (IBILCE) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Fernando Alves de Melo in research grants and scholarships supported by FAPESP.
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Cellular metabolism is mediated by signaling pathways that are regulated by enzyme activities dependent on the reversible phosphorylation of the amino acid side chain. In this way, tyrosine kinase proteins (PTKs) and tyrosine phosphatase proteins (PTPs) are pivotal in the regulation of metabolism, gene expression, growth, division and cellular differentiation. Once phosphorylated, PTKs re…
Cell metabolism is mediated by signaling pathways that are up regulated through enzymatic amino acids side chain phosphorylation dependent. So Protein Tyrosine Kinases (PTKs) play pivotal role on gene expression, cellular growth, division and differentiation, among others. Once phosphorylated, PTKs recruits protein partners such as Grb2, Shc, Ras, etc. to build up early signaling complexe…
Cell signaling is regulated by enzymatic activities through reversible phosphorylation of amino acids side chains. In this way, Protein Tyrosine Kinases (PTKs) rule the regulation upon cell proliferation, cell-cycle, growth, migration and differentiation. In many cases kinases and phosphatases, like Shp2, work together. Once phosphorylated, PTKs do the recruitment of partners like Grb2, S…
The Small-Angle X-ray Scattering (SAXS) technique plays a crucial role in structural biology, particularly in the study of macromolecules such as proteins and protein complexes in solution. Its primary importance lies in its ability to provide information about the conformation, size, and dynamics of molecules under conditions that mimic the natural physiological environment. Unlike other…
| 1 / 1 | Ongoing grants |
| 3 / 2 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 6 / 5 | All research grants and scholarships |
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