Abstract
Protein domains are segments with stable and independent folding (Richardson, 1981; Dootlitle, 1995; Porter e Rose, 2012). Based on this definition, the structure of the (beta/alpha)8 barrels proteins was shown to be composed by two domains corresponding to its N- and C-terminal halves. In agreement, the analysis of the contact map of the beta-glucosidases GH1, also (beta/alpha)8 barrels,…