Abstract
Recent studies have shown that the O-GlcNacylation, a post-translational modification of proteins, analogous to phosphorylation, involves the incorporation of O-GlcNac (O-linked N-acetylglucosamine ²-), on serine and threonine residues. It is controled by OGT and it modifies and regulates cytoplasmic and nuclear target proteins functions. The UDP-GlcNac, the substrate used by OGT for O-Gl…