Abstract
Single nucleotide polymorphisms (SNPs, rs12979860 e rs8099917) near the IL28B gene responsible for the production of interferon lambda (IFN ») have been associated with failure in antiviral innate immunity, treatment with PEG-IFN± and ribavirin and sustained virological response in hepatitis C. These polymorphisms have been studied in human T-lymphotropic virus (HTLV-1) infected individua…