Abstract
Propofol acts as central nervous system depressant, activating receptors of the gamma-aminobutyric acid (GABA), inhibiting N-methyl-D-aspartate receptor and modulating the calcium influx. It is widely used for performing anesthesia or to provide sedation in Intensive Care Units. The syndrome of continuous infusion of propofol has been reported to be related to high doses and prolonged adm…