Abstract
Primary Macronodular Adrenal Hyperplasia (PMAH) is one of the causes of Cushing's syndrome. It is characterized by the presence of functioning in the adrenal benign macronodules (usually> 1 cm) and sustained by increased production of cortisol, independent of circulating ACTH pituitary. The PMAH may present sporadically or be inherited (familial) with clinical manifestation mainly between…