Letícia Schefer in research grants and scholarships supported by FAPESP.
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Although obtaining in vitro produced embryos (IVP) is an animal biotechnology widely used in research and for commercial purposes in Brazil and the world, such embryos are still of inferior quality compared to those produced in vivo. The greater accumulation of lipids in embryos produced in vitro has been suggested as one of the causes of this lower quality. Classically, cell lipolysis is…
Bovine oocytes and blastocysts produced in vitro have darker cytoplasm as a result of higher lipid accumulation in relation to embryos produced in vivo. This characteristic has been associated with a lower quality of the in vitro produced embryo and consequently to higher sensitivity to cryopreservation. Increasing knowledge on the control of lipid metabolism in oocytes may cause changes …
Previous studies have shown that bovine cumulus-oocyte complexes (COCs), express transcripts for several enzymes of the cGMP pathway including those for its synthesis (GUCY1B3), degradation (PDE5A) and signaling (PKG1 and PKG2), and that FCS in IVM medium affects the expression of some of these transcripts, as well as decreases cGMP levels. Inhibition of cGMP hydrolysis with PE% inhibitor…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
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