CV Lattes
ORCID
Abstract
In the last few years acute lymphoblastic leukemia (ALL) patients prognosis have been significantly improved, however, some subgroups, such as Ph positive leukemia frequently experience relapse and low cure rates, representing a challenge. The Ph positive leukemias show the BCR-ABL fusion gene, that arises from a translocation between chromosomes 9 and 22. This mutation gives rise to the …