Abstract
In Leishmania infection, along with the specific immune response, nonspecific factors participate in its evolution as growth factors, including the Insulin-Like Growth Factor-I (IGF-I). In previous studies carried out by the group of Profª Drª Hiro Goto, it was demonstrated that extrinsic IGF-I acts as a promoter of proliferation and growth of parasites of the genus Leishmania and acts in…