CV Lattes
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Universidade Federal do ABC (UFABC). Centro de Matemática, Computação e Cognição (CMCC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Bacharelado em Química c/ Atribuições Tecnológicas from Centro Universitário Fundação Santo André (2007), graduation at Licenciatura em Química from Centro Universitário Fundação Santo André (2006), master's at Ciência Tecnologia / Química from Universidade Federal do ABC (2014) and doctorate at Ciência e Tecnologia/Química from Universidade Federal do ABC (2019). He is currently pesquisador doutor colaborador at Universidade Federal do ABC. Has experience in Chemistry, acting on the following subjects: diabetes, dpp-4, docking, sars-cov-2 and tmem176b. (Source: Lattes Curriculum)
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TMEM176 proteins are an ion channel expressed in immune cells and certain types of cancer. The transmembrane proteins TMEM176A and 176B belong to the CD20/Fc-µRI² and membrane-spanning 4A (MS4A) family of proteins. Human TMEM176B (also known as LR8) was first discovered in human lung fibroblasts, and was recently associated in human small cell lung carcinoma . Similar to TMEM176A, the lev…
Seeking to understand the action mechanism of dipeptidyl peptidase-4 (DPP-4) and the main interactions between bioactive ligands and selected target, this project proposes a detailed analysis of the enzyme structure in order to understand the main characteristics of the active site, as well as the influence of structural water in the reaction process and the essential aminoacids into the …
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