CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ) (Institutional affiliation for the last research proposal) Birthplace: Brazil
She has degree in Veterinary Medicine from the University of São Paulo (1994) and a PhD in Experimental and Comparative Pathology (2012). She is currently a Professor at the Department of Pathology at the School of Veterinary Medicine and Animal Science at the University of São Paulo. She has experience in Veterinary Medicine, with emphasis on Laboratory Animal Science, working mainly on the following topics: mouse genetics and mutation characterization, management and breeding of laboratory rodents, refinement of experimental procedures in laboratory animals. (Source: Lattes Curriculum)
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Analysis of mutations in murine models may reveal new functions for known genes, identify genes underlying orthologous human diseases - in which the causal gene has not yet been identified - as well as provide the investigation of new relevant phenotypes. The spontaneous mutation tremor (tr), autosomal recessive, was identified in the colony of Swiss mice of the laboratory animal facility…
The recessive mutant mouse named bate palmas (bapa) - claps in Portuguese, which presents balance impairment and incoordination, was originated from an ENU (N-Ethyl-N-nitrosourea) mutagenesis program. The lysine (K) -specific methyltransferase 2D gene (KMT2D), located on chromosome 15, was identified as a candidate gene by exome sequencing. The mutation was confirmed by Sanger DNA sequenc…
The recessive mutation mergulhador ("diver"; symbol - mlh), which was originated from an ENU mutagenesis program, severely affects the swimming abilities of affected mice when put in a water tank. Under normal conditions, mlh/mlh mice exhibit head tilting but show no other behavioral abnormalities such as circling or head tossing. The locus for mlh is on chromosome 5 (Chr 5) and was ident…
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| 2 / 2 | Completed scholarships in Brazil |
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