Marina Dorigatti Borges in research grants and scholarships supported by FAPESP.
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Iron overload can occur in patients undergoing successive blood transfusions, such as patients with thalassemia and sickle cell anemia. Iron overload cardiomyopathy is described as dilated cardiomyopathy, characterized by left ventricular hypertrophy and reduced left ventricular ejection fraction. Deferiprone (DFP) is a hydroxypiridinone derivatived iron chelator, approved for iron overlo…
Aceruloplasminemia is an autosomal recessive inherited disease that leads to the accumulation of iron in the brain. Diagnosis of the disease is made with the absence of serum ceruplasmina detection associated with neuroimaging tests suggestive of iron overload in the brain, usually associated with other laboratory abnormalities, such as high levels of ferritin, light microcytic and low se…
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