Abstract
The acute lymphoblastic leucemia (ALL) is an aggressive cancer characterized by the overproduction and accumulation of immature lymphoid precursors, which proliferate and replace normal hematopoietic cells in the bone marrow. ALL can be an acute lymphoblastic leukemia T (T-ALL) or acute lymphoblastic leukemia B (B-ALL). Approximately 35% of ALL cases are associated with the presence of ch…