Abstract
In periodontal diseases (PD) there is loss of bone homeostasis culminating in alveolar bone resorption. Recent studies have revealed the mechanisms of action of the autonomic nervous system on bone metabolism. The adrenergic via acts principally favoring bone loss as cholinergic via favors bone mass accrual. Cholinergic agonist drugs, such as inhibitors of the enzyme that degrades acetylc…