Abstract
Cardiovascular diseases are the leading cause of death worldwide, and atherosclerosis is its major underlying cause. Atherosclerosis is characterized by a chronic inflammatory process that begins with accumulation of Low-Density Lipoprotein (LDL) in subendothelial space. After that, LDL is oxidized and phagocytized by macrophages, turning them into foam cells that accumulate free, esterif…