Abstract
Alcoholic cardiomyopathy is a disease caused by excessive consumption of ethanol and can lead to progressive cardiac dysfunction and heart failure. Ethanol consumption is associated with increased systemic production of pro-inflammatory cytokines such as tumor necrosis factor (TNF-alpha). TNF-alpha R1 receptors (TNFR1) induces activation of the enzyme NAD(P) H oxidase with consequent incr…