Abstract
The Present investigation is intended to better understand the molecular mechanisms involved in priapism induced by the spider toxins Tx2-6 and Tx2-5 found in the venom of the spider Phoneutria nigriventer. This spider venom contains a large number of toxins with diverse pharmacological actions. The Tx2-5 and Tx2-6 were identified in this laboratory as responsible for the priapism and are…