Guilherme Afonso Vergara

Sociedade Beneficente Israelita Brasileira Albert Einstein (SBIBAE). Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

Abstract
Central Nervous System (CNS) Cancers, despite their low incidence rates, are highly lethal and clinically heterogeneous tumors. The vast majority of primary CNS tumors are diagnosed as gliomas, followed by Meningiomas and other less common types such as Craniopharyngiomas, Hemangiomas and Gangliogliomas. To date, the available biomarkers are not enough to underscore the characteristics th…
Necrotic cell death pathways & immunemodulation: identification of predictive markers in central nervous system tumors, BP.DR
Abstract
Necroptosis is a cell death pathway characterized by plasma membrane rupture and cytoplasmic content leakage, leading to a pro-inflammatory environment. Membrane disruption is mediated by MLKL when activated by RIPK3 phosphorylation. RIPK3, in turn, can be activated by a wide variety of stimuli, including but not limited to Death and Toll-like receptors, viral sensors, DNA damage and chem…
RIPK3 and MLKL expression in rectal cancer cells and their sensitivity to canonical and alternative Necroptotic pathways, BP.MS

Source:Lattes Curriculum

CV Lattes ORCID

2 / 2	Completed scholarships in Brazil

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Abstract

Abstract