Abstract
Agrin is a high molecular weight heparan sulfate proteoglycan found with high protein expression in various types of cancer, such as squamous cell carcinoma (SCC), liver cancer, lung cancer, among others. We have recently shown that agrin knockdown (shAgrin) in oral SCC cell lines (SCC9 and HSC3) decreases about 50% the cell proliferation, migration and invasion, as well as decreases the …