CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade Estadual de Maringá (2012), master's at Imunologia Básica e Aplicada from Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo (2015) and doctorate at Hermelin Brain Tumor Center from Henry Ford Health System (2018). Has experience in General Biology, acting on the following subjects: monogenea, ictioparasitologia, imunogenética and hematologia. (Source: Lattes Curriculum)
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DNA methylation is a process involved in gene stability, genomic organization and developmental process and has being associated with many diseases, such as cancer. In cancer, a genome-wide hypomethylation at non-promoters and focal hypermethylation at given CpG islands (promoters) are observed, responsible for overexpression of oncogenes and silencing of tumor suppressor genes, respectiv…
Cancer cells are marked by deregulation of gene expression and genomic instability attributed to genetic mutations and epigenetic alterations that determine active and repressed chromatin. Among the epigenetic modifications, DNA methylation deregulation is a hallmark in cancer. Non-tumoral cells present genome-wide methylation, and hypomethylation in CpG islands (CGIs). In contrast, some …
| 1 / 1 | Completed scholarships in Brazil |
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