Abstract
The recessive mutant mouse named bate palmas (bapa) - claps in Portuguese, which presents balance impairment and incoordination, was originated from an ENU (N-Ethyl-N-nitrosourea) mutagenesis program. The lysine (K) -specific methyltransferase 2D gene (KMT2D), located on chromosome 15, was identified as a candidate gene by exome sequencing. The mutation was confirmed by Sanger DNA sequenc…