Abstract
Acute myeloid leukemia (AML) can be defined, in most cases, as a cluster of diseases of a sporadic nature and represents failure in the maturation of myeloid cells, with the expansion of the immature lineage in blood, marrow and other tissues. Of the many genetic changes that can result in the disease, the mutation in the FLT3 gene in the form of internal tandem duplications (ITD) appears…