Abstract
The Bicaudal C homolog 1 (BICC1) is a RNA-binding protein characterized by three K Homology domains in the N terminal end (KH1, KH2 and KH3 domains) which are responsible for the RNA-binding activity, and a Sterile Alpha Motif at the C-terminal end (SAM domain) which was related to the promotion of protein-protein interaction. The protein has been studied by its role in polycystic kidney …