Abstract
Osteosarcomas, classified as mesenchymal tumors, described as a malignant bone tumor accounting for 80% of tumors, very common in dogs, cats and humans. Our results "in vitro" suggests that treatment of MSCs with fetal canine bone marrow (MSC) with bone morphogenetic protein (rhBMP-2) was able to induce the osteogenic potential and p53-mediated tumor suppression. "In vivo" we observe that…