Abstract
Interleukin-10 (IL-10) is an anti-inflammatory and immunosuppressive cytokine produced by several cell types, including macrophages, dendritic cells and various T-cell subgroups. This cytokine is released with the aim of modulating the synthesis of pro-inflammatory cytokines ensuring that no exacerbated inflammation occurs. However, polymorphisms in the IL-10 promoter region may be relate…