Abstract
EPPIN (Epididymal protease inhibitor) is a member of the WFDC (Whey acidic protein-type four-disulfide core) gene family abundantly expressed in the testis and epididymis. EPPIN is found on the surface of spermatozoa, where it plays a role on sperm motility after ejaculation. It has been demonstrated that blocking EPPIN on the surface of human ejaculate spermatozoa with anti-EPPIN antibod…