Abstract
Galectin-9 (Gal-9) belongs to a protein family characterized by a conserved carbohydrate recognition domain (CRD) of approximately 135 amino acids responsible for its binding to ²-galactoside sugars. In experimental models of inflammation, Gal-9 has been pointed as an anti-inflammatory mediator. However, in relation to its mechanisms of action in allergy, Gal-9 can play a dual role, eithe…