Abstract
Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi and affects around 6 to 7 million people worldwide. T. cruzi cell invasion can occur by metacyclic and blood trypomastigote forms and extracellular amastigote forms (EAs) which is originated by premature lysis of host cell or by extracellular differentiation of bloodstream trypomastigotes. EAs are able to invade and co…