CV Lattes
ORCID
Abstract
The interior of root canals of teeth with pulp necrosis presents a complex and adequate ecological niche for the development of polymicrobial endodontic infections. The main virulence factor of gram-negative bacteria is lipopolysaccharide (LPS), also known as endotoxins; and in gram-positive bacteria is the lipoteichoic acid (LTA). Root canals with necrotic pulp are considered infectious …